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Epertinib hydrochloride
CAS No. 2071195-74-7
Epertinib hydrochloride ( S-22611 hydrochloride )
Catalog No. M23929 CAS No. 2071195-74-7
Epertinib hydrochloride shows potent antitumor activity.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 129 | In Stock |
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| 5MG | 222 | In Stock |
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| 10MG | 356 | In Stock |
|
| 25MG | 601 | In Stock |
|
| 50MG | 858 | In Stock |
|
| 100MG | 1161 | In Stock |
|
| 500MG | 2331 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEpertinib hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionEpertinib hydrochloride shows potent antitumor activity.?
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DescriptionEpertinib hydrochloride shows potent antitumor activity.?Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
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SynonymsS-22611 hydrochloride
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR;HER4;HER2
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Research Area——
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Indication——
Chemical Information
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CAS Number2071195-74-7
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Formula Weight596.5
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Molecular FormulaC30H28Cl2FN5O3
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (209.56 mM; Need ultrasonic)
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SMILESCC#C/C(=N\OC[C@H]1COCCN1)/C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tanaka H, et al. Preclinical antitumor activity of S-222611, an oral reversible tyrosine kinase inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2. Cancer Sci. 2014 Aug;105(8):1040-8.
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